NMN 500
THE PRECURSOR
500 mg beta-NMN. One capsule. A dose studied directly in humans. NMN is a precursor your body uses to make NAD+, a coenzyme central to cellular energy metabolism.*
*Using globally sourced ingredients.
If your first order is not right for you, email us within 60 days for a refund.
The people and evidence behind this page
How this page gets checked
We maintain a working library of more than 1,500 studies across NMN, NAD+ and resveratrol, then map product claims to the relevant evidence.
Study-specific figures on this page link to the source behind them.
Why we kept NMN 500 simple
I wanted NMN 500 to stay simple: one active ingredient, 500 mg beta-NMN, a dose used directly in human studies, with the formula and testing easy to inspect.
Florian Rivas, Founder of CELLSHE · Longevity Educator · Read our story
Made, tested and documented
Using globally sourced ingredients in a GMP-certified, FDA-registered facility.
Performed in ISO/IEC 17025 accredited laboratories.
500 mg beta-NMN, a vegetable capsule and three named supporting ingredients.
Non-hormonal support for NAD+ biosynthesis, healthy NAD+ levels and daily cellular vitality.*
The full specification
500 mg per day has been studied directly in humans. In a randomized one-month study, the same daily amount used in NMN 500 increased average whole-blood NAD+ versus placebo. Read the study
The Certificate of Analysis
Independent testing has found that some commercial NMN products contained materially different amounts from their labels. CELLSHE makes its Certificate of Analysis available so you can inspect the testing documentation yourself.
What to look for in an NMN lab report
What NMN 500 supports
One active ingredient, a human-studied daily amount and claims focused on the strongest areas of NMN evidence.*
Supports your body’s natural production of NAD+.*
Helps maintain healthy NAD+ levels.*
Supports daily cellular vitality through the NAD+ pathway.*
Supports healthy physical function in midlife and older adults.*
500 mg. One capsule. One clear routine.
Choose one time, or subscribe for the lower price, free U.S. shipping and the complete CELLSHE Circle.
How it works
One capsule provides the complete daily serving.
NMN supports the body’s natural NAD+ biosynthesis pathways.*
NAD+ is a coenzyme central to normal cellular energy metabolism.*
Choose your starting point
Both are complete CELLSHE options. The right choice depends on how focused or broad you want the routine to be.
What human studies measured
Human trials used consistent daily dosing. NMN 500 provides the full 500 mg serving in one capsule.
At 500 mg per day, average whole-blood NAD+ was 41.7 µM versus 23.8 µM with placebo. Study
A dose-ranging trial found higher blood NAD+ across 300, 600 and 900 mg per day, with the highest levels in the 600 and 900 mg groups. Study
In one 12-week study, blood NAD+ returned toward baseline four weeks after NMN was stopped. Study
The clearest result at 500 mg
The study measured whole-blood NAD+ after 30 days of daily supplementation.
What the published trial measured
Average whole-blood NAD+ at day 30 with 500 mg NMN per day versus placebo. Read the study
These are average study results. Individual responses vary. Human evidence is strongest for NAD+ biomarkers, while functional findings are more modest and vary between studies.
The CELLSHE standard
What you can verify
See the human evidence behind the claims, the laboratory report behind the testing and every active amount on the label.
Inside NMN 500
Premium learning. A routine built around your life. Real human support.
Included with every subscription
Your NMN 500 subscription includes the complete CELLSHE Circle: premium learning each month, a personalized routine blueprint, a private monthly routine review and a human concierge. The membership is included at no additional cost.
Four parts of the CELLSHE Circle
Explore one healthy-aging subject through the format that best fits it, including written lessons, video, quizzes, interactive tools, worksheets, trackers or printable resources.
Start at module one whenever you join. Receive the next module each month.
Timing, habit anchors, reminders and fallback options built around your mornings, meals, work and travel.
Update it whenever your schedule changes.
Use a focused one-to-one conversation to solve missed days, adapt around travel or work and turn the latest module into realistic next steps.
Leave with clear priorities and a practical plan.
Ask about NMN 500, your routine, the monthly module or your membership.
A real person reads the full message and replies within one business day.
One premium module each month. Everyone begins with module one and builds from there.
The learning path keeps growing. Module formats change with the subject, and the material is reviewed as the evidence develops.
Your first ninety days
A real person shows you where to begin and how to use the Circle.
Timing, habit anchors, reminders and fallback options are built around your real week.
The Protein Rethink begins the learning path with evidence, practical decisions and useful tools.
Tell us what is working, where the friction is and what would make the routine easier.
Refine the blueprint, apply the module and leave with a clear next step.
Two ways to buy
One-time
$49.00
Subscription · the Circle
$39.00/mo
Members also get
Your friend receives $15 toward a qualifying order, and you receive $15 when the referral qualifies.
Pause, skip or cancel from your account, or email us before the next shipment. You stay in control of the routine.
Have a question before joining? Email us and a real person will help.
Choose your NMN 500 routine
A human-studied daily amount, one active ingredient, independent third-party testing and a Certificate of Analysis available for review.
How to take NMN 500
One capsule provides the full 500 mg daily amount.
Morning works well for many routines. Consistency matters more than a specific clock time.
Take the next capsule at the usual time. Do not double the serving.
NMN compared with NR
Both NMN and NR can raise circulating NAD-related measures. They enter the pathway differently and do not produce identical metabolite profiles.
500 mg in one capsule
CELLSHE chose NMN for this formula because the exact 500 mg daily amount has been studied directly in humans.
A different NAD+ precursor
NR has its own human evidence base and produces a different metabolite profile. Pathway position alone does not establish better outcomes.
NMN 500 questions
NMN 500 supports your body’s natural NAD+ production, helps maintain healthy NAD+ levels, supports the NAD+ pathway behind normal cellular energy metabolism and supports daily cellular vitality.*
In a randomized one-month study, average whole-blood NAD+ at day 30 was 41.7 µM with 500 mg per day NMN versus 23.8 µM with placebo. CELLSHE NMN 500 provides the same daily amount. The study tested NMN, not the finished CELLSHE product. Read the study
NMN is designed for daily NAD+ pathway support rather than a stimulant-style effect. Some people notice changes in how they feel and others do not. Human evidence is strongest for measurable NAD+ biomarkers.*
Human studies have measured NAD-related biomarkers after 30, 60 and 84 days of daily use. The clearest result at the CELLSHE daily amount comes from 30 days. These are study timelines, not a guarantee of an individual response. See the 30-day study
Five hundred milligrams is within the range examined in short-term human studies and has been tested directly as a daily amount in a randomized one-month study. It also fits into one capsule, which keeps the routine simple. Human research has examined several other daily amounts as well. See the dose-ranging trial
Short-term human trials have generally found NMN well tolerated over weeks to months. A 2026 meta-analysis found no overall increase in total adverse events across the short-term randomized NMN trials it pooled. Rare, delayed and long-term risks need more study. Speak with a healthcare professional before use if you are pregnant, nursing, taking medication or managing a medical condition. Read the meta-analysis
Both are NAD+ precursors and both can raise circulating NAD-related measures. They produce different metabolite profiles. CELLSHE chose NMN and provides a directly studied 500 mg daily amount in one capsule. Pathway position alone does not establish superior outcomes. Read the comparison study
Review the complete Supplement Facts panels so you do not duplicate NMN or overlapping ingredients. CELLSHE does not make a universal compatibility promise. Ask a healthcare professional to review the full routine if you take medication, have a medical condition, are pregnant or nursing.
The value includes a complete 500 mg serving in one capsule, one fully disclosed active ingredient, independent third-party testing, accessible quality documentation and human support after checkout. Subscribers also receive the lower member price, free U.S. shipping and the complete CELLSHE Circle.
The subscription includes the lower member price, free U.S. shipping and the complete CELLSHE Circle. Members receive premium learning each month, a personalized routine blueprint, one private routine review each month, a human concierge, member offers and a price locked at the rate they joined. Pause, skip or cancel anytime.
Eligible first orders are covered by the 60-Day Guarantee. Email CELLSHE within 60 days of your first order for a refund. You keep the bottle.
Every active amount is printed on the label, and the Certificate of Analysis is available on this page or by request so you can inspect the available testing documentation. Independent research has found that the measured NMN content of some commercial supplements differed materially from the label, which is why CELLSHE treats testing transparency as part of the product. Read the testing study
Ready to make NMN part of your routine?
Choose one time, or subscribe for the lower price, free U.S. shipping and the complete CELLSHE Circle.
The CELLSHE range
Each CELLSHE product has a distinct role. Start with one, or bring NMN, resveratrol and creatine together with the Cellular Trio.
You are here
NMN 500
500 mg beta-NMN in one capsule to support cellular energy and healthy NAD+ levels.*$39.00/monthabout $1.30 a dayOne-time $49.00You are viewing this →
Antioxidant support
Resveratrol 600
Standardized Japanese knotweed extract for focused antioxidant support.*$35.00/monthabout $1.20 a dayOne-time $39.00View Resveratrol 600 →
Strength & active aging
Creatine Monohydrate
5 g of high-purity creatine monohydrate per serving to support strength, and physical capability through midlife.*$29.00/50 daysabout $0.60 a dayOne-time $35.00View Creatine Monohydrate →
Three-part routine
The Cellular Trio
NMN 500, Resveratrol 600 and Creatine Monohydrate together in one bundle for cellular energy, antioxidant support and midlife strength.*$109.00
One-time bundleView The Cellular Trio →
*These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
CELLSHE products are intended for healthy adults. Consult your healthcare provider before starting any new supplement, especially if you are pregnant, nursing, take medications, or have a medical condition. Not for use by individuals under 18 years of age. Keep out of reach of children. Discontinue use and consult a healthcare professional if any adverse reaction occurs.
