Human evidence first
Human trials and high-quality syntheses carry the most weight when they can answer the question.
CELLSHE supplement guides
Understand the supplement before you buy the supplement.
CELLSHE builds in-depth, evidence-based supplement guides for women who want a clear answer before adding something to their routine.
Each guide starts with human research, separates women-specific evidence from broader evidence, and answers the practical questions that matter: what the supplement does, how much is typically used, what is relevant after 40 and menopause, what safety data show, and which popular claims are ahead of the science.
These are decision guides, not product roundups.
Choose your guide
You do not need to understand every supplement. You need the right evidence for the one you are considering.
Choose a guide below for the full answer, practical protocol, safety questions, and human research behind it.
NAD+ · Midlife · Human evidence
What does NMN actually do for women, and what has been studied after 40?
Start here for the women-specific human trials, NAD+ biology, doses used in research, menopause context, safety, and a clear framework for choosing an NMN supplement without turning every early signal into a benefit claim.
Strength · Muscle · Menopause · Safety
Is creatine actually useful for women, especially in midlife?
Get the practical answer on strength, resistance training, lean mass, women over 40, menopause, 3-5 g/day dosing, water weight, kidneys, hair, safety, and why creatine monohydrate remains the reference form.
Not sure where to start? Choose the guide for the supplement you are actively considering. Each page is designed to stand on its own, so you can get a useful answer without reading the entire CELLSHE library.
How CELLSHE builds these guides
A useful supplement guide should tell you what deserves confidence, what remains uncertain, and what that means for a real decision. More citations are not useful if they leave you more confused than when you arrived.
Human trials and high-quality syntheses carry the most weight when they can answer the question.
We identify direct evidence in women instead of silently treating mixed-sex research as women-specific.
Positive, mixed, null, and emerging results are separated so one favorable study cannot become the whole story.
Dose, timing, safety, life stage, product form, and common concerns are translated into usable decisions.
Keep exploring
The Supplement Guides are one layer of CELLSHE's evidence system. The Science page explains the research behind our ingredient education. Our Standard explains how products and claims are documented. The Journal goes deeper on individual questions, and the Aging Well Guide focuses on the habits that matter beyond supplements.
CELLSHE educational content is general information, not medical advice or a substitute for care from your own clinician.